The filling system is designed to deliver accurate and consistent dosing of pharmaceutical liquids into pre-sterilized syringe barrels. The system incorporates controlled filling operations to ensure uniform product dispensing while minimizing product loss and maintaining the integrity of sensitive formulations.
The filling system can be configured with suitable pump technologies based on product viscosity, filling volume, and formulation requirements.
Volumetric filling for accurate and consistent dosing.
Controlled piston movement for precise filling volume adjustment.
Suitable for pharmaceutical liquids with varying viscosities.
Designed for repeatable filling performance during continuous operation.
Adjustable filling parameters to accommodate different product requirements.
Gentle product dispensing through controlled compression of flexible tubing.
Reduced direct contact between the product and mechanical pump components.
Suitable for sensitive pharmaceutical formulations.
Adjustable pump speed for controlled liquid dispensing.
Supports convenient product changeover through replaceable tubing arrangements.
The in-process control system is designed to monitor filling accuracy by verifying the weight of filled syringes. It supports consistent dosing performance and helps identify filling deviations during production.
100% IPC capability for filling accuracy verification.
Pre-fill and post-fill weighing for net product weight calculation, where configured.
Automatic identification of syringes outside predefined filling weight limits.
Monitoring of filling weight variations during production.
Integration with the filling control system for process monitoring.
Automatic rejection of non-conforming syringes, where equipped.
Filling weight data recording for batch documentation and process evaluation.
The vacuum stoppering system is designed to insert rubber stoppers into filled syringe barrels under controlled vacuum conditions. The process helps minimize air entrapment between the liquid product and stopper while maintaining consistent stopper positioning.
Vacuum-assisted stopper insertion for controlled and repeatable placement.
Designed to minimize air entrapment within filled syringes.
Controlled stopper insertion depth based on syringe specifications.
Automated stopper feeding and positioning arrangements.
Suitable for different syringe barrel and stopper configurations.
Consistent stopper placement to support product containment and closure integrity.
Stoppering operations synchronized with the filling process for continuous production.
The stopper positioning system supports accurate insertion and verification of rubber stoppers within the syringe barrel to maintain consistent product packaging quality.
Controlled stopper positioning within the syringe barrel.
Adjustable insertion depth according to syringe format.
Stopper presence verification before insertion, where configured.
Monitoring of stopper insertion parameters.
Detection of incorrectly positioned stoppers, where equipped.
Supports consistent stopper placement across production batches.
| Precision Filling | Accurate liquid dosing with servo-driven filling technology |
| Filling Pump Technologies | Rotary piston and peristaltic filling pump options |
| In-Line Weighing & IPC | Filling accuracy verification and process monitoring |
| Vacuum Stoppering | Controlled stopper insertion with minimized air entrapment |
| Inline Weighing & IPC | 100% weight verification, monitoring and rejection |
High-Speed Performance: Production capacity of up to 200 syringes/min.
Advanced Aseptic Protection: Available with oRABS, cRABS, and isolator configurations.
Automated Syringe Handling: Smooth and controlled transfer of nested syringes throughout the process.
Flexible Syringe Compatibility: Designed to accommodate different syringe formats with suitable change parts.
Integrated Process Monitoring: Monitoring of critical filling and stoppering parameters.